Cargando…

Circulating Dickkopf‐1 in Diabetes Mellitus: Association With Platelet Activation and Effects of Improved Metabolic Control and Low‐Dose Aspirin

BACKGROUND: Dickkopf‐1 (DKK‐1) is a major regulator of the Wnt signaling pathway, involved in inflammation, atherogenesis, and the regulation of glucose metabolism. Because platelets are major contributors to circulating levels of DKK‐1 in other clinical settings, we aimed at characterizing the plat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lattanzio, Stefano, Santilli, Francesca, Liani, Rossella, Vazzana, Natale, Ueland, Thor, Di Fulvio, Patrizia, Formoso, Gloria, Consoli, Agostino, Aukrust, Pål, Davì, Giovanni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310390/ https://www.ncbi.nlm.nih.gov/pubmed/25037197 http://dx.doi.org/10.1161/JAHA.114.001000

Ejemplares similares

Circulating Myeloid‐Related Protein–8/14 is Related to Thromboxane‐Dependent Platelet Activation in Patients With Acute Coronary Syndrome, With and Without Ongoing Low‐Dose Aspirin Treatment
por: Santilli, Francesca, et al.
Publicado: (2014)

LIGHT/TNFSF14 is increased in patients with type 2 diabetes mellitus and promotes islet cell dysfunction and endothelial cell inflammation in vitro
por: Halvorsen, Bente, et al.
Publicado: (2016)

A Complex Interaction between Rickettsia conorii and Dickkopf-1 – Potential Role in Immune Evasion Mechanisms in Endothelial Cells
por: Astrup, Elisabeth, et al.
Publicado: (2012)

Effects of liraglutide vs. lifestyle changes on soluble suppression of tumorigenesis-2 (sST2) and galectin-3 in obese subjects with prediabetes or type 2 diabetes after comparable weight loss
por: Simeone, Paola, et al.
Publicado: (2022)

Thromboxane-Dependent Platelet Activation in Obese Subjects with Prediabetes or Early Type 2 Diabetes: Effects of Liraglutide- or Lifestyle Changes-Induced Weight Loss †
por: Simeone, Paola, et al.
Publicado: (2018)

Bone Matrix Levels of Dickkopf and Sclerostin are Positively Correlated with Bone Mass and Strength in Postmenopausal Osteoporosis
por: Ueland, Thor, et al.
Publicado: (2019)

Patient perceptions of insulin therapy in diabetes self-management with insulin injection devices
por: Consoli, Agostino, et al.
Publicado: (2023)

Enhanced Lipid Peroxidation and Platelet Activation as Potential Contributors to Increased Cardiovascular Risk in the Low‐HDL Phenotype
por: Vazzana, Natale, et al.
Publicado: (2013)

CCL21 and prognosis in acute coronary syndrome
por: Ueland, Thor, et al.
Publicado: (2019)

Reduced platelet glycoprotein Ibα shedding accelerates thrombopoiesis and COX-1 recovery: implications for aspirin dosing regimen
por: Simeone, Paola, et al.
Publicado: (2022)

Low circulating pentraxin 3 levels in pregnancy is associated with gestational diabetes and increased apoB/apoA ratio: a 5-year follow-up study
por: Lekva, Tove, et al.
Publicado: (2016)

Circulating T Cell Activation and Exhaustion Markers Are Associated With Radiation Pneumonitis and Poor Survival in Non-Small-Cell Lung Cancer
por: Berg, Janna, et al.
Publicado: (2022)

Corrigendum: Circulating T cell activation and exhaustion markers are associated with radiation pneumonitis and poor survival in non-small-cell lung cancer
por: Berg, Janna, et al.
Publicado: (2022)

Aspirin Rescues Wnt-Driven Stem-like Phenotype in Human Intestinal Organoids and Increases the Wnt Antagonist Dickkopf-1
por: Dunbar, Karen, et al.
Publicado: (2020)

Circulating PCSK9 and Risk of Myocardial Infarction: The HUNT Study in Norway
por: Laugsand, Lars E., et al.
Publicado: (2016)

Platelet and mitochondrial RNA is decreased in plasma-derived extracellular vesicles in women with preeclampsia—an exploratory study
por: Lekva, Tove, et al.
Publicado: (2023)

Aortic Stiffness and Cardiovascular Risk in Women with Previous Gestational Diabetes Mellitus
por: Lekva, Tove, et al.
Publicado: (2015)

Leptin and adiponectin as predictors of cardiovascular risk after gestational diabetes mellitus
por: Lekva, Tove, et al.
Publicado: (2017)

Distinct patterns of soluble leukocyte activation markers are associated with etiology and outcomes in precapillary pulmonary hypertension
por: Lekva, Tove, et al.
Publicado: (2020)

Aspirin inhibit platelet-induced epithelial-to-mesenchymal transition of circulating tumor cells (Review)
por: LOU, XIAO-LIANG, et al.
Publicado: (2014)

Platelets, Aspirin and Cardiovascular Disease
por: Elwood, P. C.
Publicado: (1976)

Fifty years with aspirin and platelets
por: Patrono, Carlo
Publicado: (2022)

Immediate response in markers of inflammation and angiogenesis during exercise: a randomised cross-over study in heart transplant recipients
por: Yardley, Marianne, et al.
Publicado: (2017)

Fatty Acids Composition and HIV Infection: Altered Levels of n-6 Polyunsaturated Fatty Acids Are Associated with Disease Progression
por: Ueland, Thor, et al.
Publicado: (2023)

Decreased Circulating Levels of Dickkopf-1 in Patients with Exudative Age-related Macular Degeneration
por: Qiu, Fangfang, et al.
Publicado: (2017)

Inositol and antioxidant supplementation: Safety and efficacy in pregnancy
por: Formoso, Gloria, et al.
Publicado: (2019)

Old and New Biomarkers Associated with Endothelial Dysfunction in Chronic Hyperglycemia
por: Baldassarre, Maria Pompea Antonia, et al.
Publicado: (2021)

Podocan and Adverse Clinical Outcome in Patients Admitted With Suspected Acute Coronary Syndromes
por: Andersen, Thomas, et al.
Publicado: (2022)

Increased levels of NT-proBNP and troponin T 2 years after coronary artery bypass grafting complicated by mediastinitis
por: Risnes, Ivar, et al.
Publicado: (2023)

Microvascular function and inflammatory activation in Takotsubo cardiomyopathy
por: Solberg, Ole Geir, et al.
Publicado: (2023)

Reduced levels of circulating adhesion molecules in adolescents with early-onset psychosis
por: Wedervang-Resell, Kirsten, et al.
Publicado: (2020)

Correction: Magnetic Resonance Imaging Determined Visceral Fat Reduction Associates with Enhanced IL-10 Plasma Levels in Calorie Restricted Obese Subjects
por: Formoso, Gloria, et al.
Publicado: (2013)

Magnetic Resonance Imaging Determined Visceral Fat Reduction Associates with Enhanced IL-10 Plasma Levels in Calorie Restricted Obese Subjects
por: Formoso, Gloria, et al.
Publicado: (2012)

Levels and prognostic impact of circulating markers of inflammation, endothelial activation and extracellular matrix remodelling in patients with lung cancer and chronic obstructive pulmonary disease
por: Berg, Janna, et al.
Publicado: (2018)

Associations between circulating endostatin levels and vascular organ damage in systemic sclerosis and mixed connective tissue disease: an observational study
por: Reiseter, Silje, et al.
Publicado: (2015)

Osteoprotegerin Is Associated With Major Bleeding But Not With Cardiovascular Outcomes in Patients With Acute Coronary Syndromes: Insights From the PLATO (Platelet Inhibition and Patient Outcomes) Trial
por: Ueland, Thor, et al.
Publicado: (2018)

Study of pulsed electrostatic field (PESF) in the perfusion of peripheral tissues: Microangiopathy, nutrition and quality of perceiver life
por: Liani, Rossella, et al.
Publicado: (2022)

Endogenous PCSK9 may influence circulating CD45(neg)/CD34(bright) and CD45(neg)/CD34(bright)/CD146(neg) cells in patients with type 2 diabetes mellitus
por: Tripaldi, Romina, et al.
Publicado: (2021)

Vitamin D Status and Long-Term Mortality in Community-Acquired Pneumonia: Secondary Data Analysis from a Prospective Cohort
por: Holter, Jan C., et al.
Publicado: (2016)

Elevated plasma levels of plasminogen activator inhibitor‐1 are associated with risk of future incident venous thromboembolism
por: Frischmuth, Tobias, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_s6vjp72u5kmha9sa97c3das8nd