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A Simple Sperm DNA Toroid Integrity Test and Risk of Miscarriage

Current methods of analyzing sperm chromatin competency overlook the inner sperm compartment which is inaccessible to probes and reagents. By breaking the molecular protamine disulfide bridges, the DNA toroids are exposed to integrity analysis. The aim was to develop a simple nuclear toroid test and...

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Detalles Bibliográficos
Autores principales: Chan, Philip J., Orzylowska, Eliza M., Corselli, Johannah U., Jacobson, John D., Wei, Albert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310444/
https://www.ncbi.nlm.nih.gov/pubmed/25649376
http://dx.doi.org/10.1155/2015/780983