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A Simple Sperm DNA Toroid Integrity Test and Risk of Miscarriage
Current methods of analyzing sperm chromatin competency overlook the inner sperm compartment which is inaccessible to probes and reagents. By breaking the molecular protamine disulfide bridges, the DNA toroids are exposed to integrity analysis. The aim was to develop a simple nuclear toroid test and...
Autores principales: | Chan, Philip J., Orzylowska, Eliza M., Corselli, Johannah U., Jacobson, John D., Wei, Albert K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310444/ https://www.ncbi.nlm.nih.gov/pubmed/25649376 http://dx.doi.org/10.1155/2015/780983 |
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