Rapamycin Improves Palmitate-Induced ER Stress/NFκB Pathways Associated with Stimulating Autophagy in Adipocytes

Obesity-induced endoplasmic reticulum (ER) stress and inflammation lead to adipocytes dysfunction. Autophagy helps to adapt to cellular stress and involves in regulating innate inflammatory response. In present study, we examined the activity of rapamycin, a mTOR kinase inhibitor, against endoplasmi...

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Detalles Bibliográficos
Autores principales: Yin, Jiajing, Gu, Liping, Wang, Yufan, Fan, Nengguang, Ma, Yuhang, Peng, Yongde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310475/
https://www.ncbi.nlm.nih.gov/pubmed/25653476
http://dx.doi.org/10.1155/2015/272313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310475/
https://www.ncbi.nlm.nih.gov/pubmed/25653476
http://dx.doi.org/10.1155/2015/272313

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