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Inferring Active and Prognostic Ligand-Receptor Pairs with Interactions in Survival Regression Models

Modeling signal transduction in cancer cells has implications for targeting new therapies and inferring the mechanisms that improve or threaten a patient’s treatment response. For transcriptome-wide studies, it has been proposed that simple correlation between a ligand and receptor pair implies a re...

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Detalles Bibliográficos
Autores principales: Ruggeri, Christina, Eng, Kevin H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310509/
https://www.ncbi.nlm.nih.gov/pubmed/25657571
http://dx.doi.org/10.4137/CIN.S16351