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Polycomb Protein SCML2 Associates with USP7 and Counteracts Histone H2A Ubiquitination in the XY Chromatin during Male Meiosis

Polycomb group proteins mediate transcriptional silencing in diverse developmental processes. Sex chromosomes undergo chromosome-wide transcription silencing during male meiosis. Here we report that mouse SCML2 (Sex comb on midleg-like 2), an X chromosome-encoded polycomb protein, is specifically ex...

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Detalles Bibliográficos
Autores principales: Luo, Mengcheng, Zhou, Jian, Leu, N. Adrian, Abreu, Carla M., Wang, Jianle, Anguera, Montserrat C., de Rooij, Dirk G., Jasin, Maria, Wang, P. Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310598/
https://www.ncbi.nlm.nih.gov/pubmed/25634095
http://dx.doi.org/10.1371/journal.pgen.1004954