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Polycomb Protein SCML2 Associates with USP7 and Counteracts Histone H2A Ubiquitination in the XY Chromatin during Male Meiosis
Polycomb group proteins mediate transcriptional silencing in diverse developmental processes. Sex chromosomes undergo chromosome-wide transcription silencing during male meiosis. Here we report that mouse SCML2 (Sex comb on midleg-like 2), an X chromosome-encoded polycomb protein, is specifically ex...
Autores principales: | Luo, Mengcheng, Zhou, Jian, Leu, N. Adrian, Abreu, Carla M., Wang, Jianle, Anguera, Montserrat C., de Rooij, Dirk G., Jasin, Maria, Wang, P. Jeremy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310598/ https://www.ncbi.nlm.nih.gov/pubmed/25634095 http://dx.doi.org/10.1371/journal.pgen.1004954 |
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