MiR-24 Is Required for Hematopoietic Differentiation of Mouse Embryonic Stem Cells

Overexpression of miRNA, miR-24, in mouse hematopoietic progenitors increases monocytic/ granulocytic differentiation and inhibits B cell development. To determine if endogenous miR-24 is required for hematopoiesis, we antagonized miR-24 in mouse embryonic stem cells (ESCs) and performed in vitro di...

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Detalles Bibliográficos
Autores principales: Roy, Lynn, Bikorimana, Emmanuel, Lapid, Danica, Choi, Hyewon, Nguyen, Tan, Dahl, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310609/
https://www.ncbi.nlm.nih.gov/pubmed/25634354
http://dx.doi.org/10.1371/journal.pgen.1004959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310609/
https://www.ncbi.nlm.nih.gov/pubmed/25634354
http://dx.doi.org/10.1371/journal.pgen.1004959

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