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Heteromerization of Ligand Binding Domains of N-Methyl-d-Aspartate Receptor Requires Both Coagonists, l-Glutamate and Glycine

[Image: see text] NMDA receptors (NMDAR) are voltage- and glutamate-gated heteromeric ion channels found at excitatory neuronal synapses, the functions of which are to mediate the mechanisms of brain plasticity and, thereby, its higher order functions. In addition to Glu, the activation of these het...

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Detalles Bibliográficos
Autores principales: Cheriyan, John, Mezes, Christina, Zhou, Ning, Balsara, Rashna D., Castellino, Francis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310633/
https://www.ncbi.nlm.nih.gov/pubmed/25544544
http://dx.doi.org/10.1021/bi501437s