Hidden Markov Model-Based CNV Detection Algorithms for Illumina Genotyping Microarrays

Somatic alterations in DNA copy number have been well studied in numerous malignancies, yet the role of germline DNA copy number variation in cancer is still emerging. Genotyping microarrays generate allele-specific signal intensities to determine genotype, but may also be used to infer DNA copy num...

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Detalles Bibliográficos
Autores principales: Seiser, Eric L, Innocenti, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310714/
https://www.ncbi.nlm.nih.gov/pubmed/25657572
http://dx.doi.org/10.4137/CIN.S16345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310714/
https://www.ncbi.nlm.nih.gov/pubmed/25657572
http://dx.doi.org/10.4137/CIN.S16345

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