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Hidden Markov Model-Based CNV Detection Algorithms for Illumina Genotyping Microarrays
Somatic alterations in DNA copy number have been well studied in numerous malignancies, yet the role of germline DNA copy number variation in cancer is still emerging. Genotyping microarrays generate allele-specific signal intensities to determine genotype, but may also be used to infer DNA copy num...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Libertas Academica
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310714/ https://www.ncbi.nlm.nih.gov/pubmed/25657572 http://dx.doi.org/10.4137/CIN.S16345 |