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Kinesin-13 regulates the quantity and quality of tubulin inside cilia

Kinesin-13, an end depolymerizer of cytoplasmic and spindle microtubules, also affects the length of cilia. However, in different models, depletion of kinesin-13 either lengthens or shortens cilia, and therefore the exact function of kinesin-13 in cilia remains unclear. We generated null mutations o...

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Detalles Bibliográficos
Autores principales: Vasudevan, Krishna Kumar, Jiang, Yu-Yang, Lechtreck, Karl F., Kushida, Yasuharu, Alford, Lea M., Sale, Winfield S., Hennessey, Todd, Gaertig, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310739/
https://www.ncbi.nlm.nih.gov/pubmed/25501369
http://dx.doi.org/10.1091/mbc.E14-09-1354