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Single-cell variation leads to population invariance in NF-κB signaling dynamics

The activation dynamics of nuclear factor (NF)-κB have been shown to affect downstream gene expression. On activation, NF-κB shuttles back and forth across the nuclear envelope. Many dynamic features of this shuttling have been characterized, and most features vary significantly with respect to liga...

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Detalles Bibliográficos
Autores principales: Hughey, Jacob J., Gutschow, Miriam V., Bajar, Bryce T., Covert, Markus W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310747/
https://www.ncbi.nlm.nih.gov/pubmed/25473117
http://dx.doi.org/10.1091/mbc.E14-08-1267