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No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans
Non-African populations have experienced size reductions in the time since their split from West Africans, leading to the hypothesis that natural selection to remove weakly deleterious mutations has been less effective in the history of non-Africans. To test this hypothesis, we measured the per-geno...
Autores principales: | Do, Ron, Balick, Daniel, Li, Heng, Adzhubei, Ivan, Sunyaev, Shamil, Reich, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310772/ https://www.ncbi.nlm.nih.gov/pubmed/25581429 http://dx.doi.org/10.1038/ng.3186 |
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