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Mitochondrial effectors of cellular senescence: beyond the free radical theory of aging

Cellular senescence is a process that results from a variety of stresses, leading to a state of irreversible growth arrest. Senescent cells accumulate during aging and have been implicated in promoting a variety of age-related diseases. Mitochondrial stress is an effective inducer of cellular senesc...

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Detalles Bibliográficos
Autores principales: Ziegler, Dorian V, Wiley, Christopher D, Velarde, Michael C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310776/
https://www.ncbi.nlm.nih.gov/pubmed/25399755
http://dx.doi.org/10.1111/acel.12287