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Mitochondrial effectors of cellular senescence: beyond the free radical theory of aging
Cellular senescence is a process that results from a variety of stresses, leading to a state of irreversible growth arrest. Senescent cells accumulate during aging and have been implicated in promoting a variety of age-related diseases. Mitochondrial stress is an effective inducer of cellular senesc...
Autores principales: | Ziegler, Dorian V, Wiley, Christopher D, Velarde, Michael C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310776/ https://www.ncbi.nlm.nih.gov/pubmed/25399755 http://dx.doi.org/10.1111/acel.12287 |
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