SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate

Specification of primordial germ cells (PGCs) marks the beginning of the totipotent state. However, without a tractable experimental model, the mechanism of human PGC (hPGC) specification remains unclear. Here, we demonstrate specification of hPGC-like cells (hPGCLCs) from germline competent pluripo...

Descripción completa

Detalles Bibliográficos
Autores principales: Irie, Naoko, Weinberger, Leehee, Tang, Walfred W.C., Kobayashi, Toshihiro, Viukov, Sergey, Manor, Yair S., Dietmann, Sabine, Hanna, Jacob H., Surani, M. Azim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310934/
https://www.ncbi.nlm.nih.gov/pubmed/25543152
http://dx.doi.org/10.1016/j.cell.2014.12.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310934/
https://www.ncbi.nlm.nih.gov/pubmed/25543152
http://dx.doi.org/10.1016/j.cell.2014.12.013

Ejemplares similares