Cargando…

SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate

Specification of primordial germ cells (PGCs) marks the beginning of the totipotent state. However, without a tractable experimental model, the mechanism of human PGC (hPGC) specification remains unclear. Here, we demonstrate specification of hPGC-like cells (hPGCLCs) from germline competent pluripo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Irie, Naoko, Weinberger, Leehee, Tang, Walfred W.C., Kobayashi, Toshihiro, Viukov, Sergey, Manor, Yair S., Dietmann, Sabine, Hanna, Jacob H., Surani, M. Azim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310934/ https://www.ncbi.nlm.nih.gov/pubmed/25543152 http://dx.doi.org/10.1016/j.cell.2014.12.013

Ejemplares similares

A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons
por: Sybirna, Anastasiya, et al.
Publicado: (2020)

Testing the role of SOX15 in human primordial germ cell fate
por: Pierson Smela, Merrick, et al.
Publicado: (2019)

Germ cell specification and pluripotency in mammals: a perspective from early embryogenesis
por: Irie, Naoko, et al.
Publicado: (2014)

Principles of early human development and germ cell program from conserved model systems
por: Kobayashi, Toshihiro, et al.
Publicado: (2017)

A PAX5-OCT4-PRDM1 Developmental Switch Specifies Human Primordial Germ Cells
por: Fang, Fang, et al.
Publicado: (2018)

Preformation and epigenesis converge to specify primordial germ cell fate in the early Drosophila embryo
por: Colonnetta, Megan M., et al.
Publicado: (2022)

Epigenetic resetting in the human germ line entails histone modification remodeling
por: Gruhn, Wolfram H., et al.
Publicado: (2023)

Reprogramming Primordial Germ Cells into Pluripotent Stem Cells
por: Durcova-Hills, Gabriela, et al.
Publicado: (2008)

Dnd Is a Critical Specifier of Primordial Germ Cells in the Medaka Fish
por: Hong, Ni, et al.
Publicado: (2016)

Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors
por: Chen, Di, et al.
Publicado: (2019)

Rebuilding Pluripotency from Primordial Germ Cells
por: Leitch, Harry G., et al.
Publicado: (2013)

A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development
por: Tang, Walfred W.C., et al.
Publicado: (2015)

PRMT5 Protects Genomic Integrity during Global DNA Demethylation in Primordial Germ Cells and Preimplantation Embryos
por: Kim, Shinseog, et al.
Publicado: (2014)

X Chromosome Activity in Mouse XX Primordial Germ Cells
por: Chuva de Sousa Lopes, Susana M, et al.
Publicado: (2008)

Tracing the transitions from pluripotency to germ cell fate with CRISPR screening
por: Hackett, Jamie A., et al.
Publicado: (2018)

The balance between NANOG and SOX17 mediated by TET proteins regulates specification of human primordial germ cell fate
por: Li, Zili, et al.
Publicado: (2022)

Proximal visceral endoderm and extraembryonic ectoderm regulate the formation of primordial germ cell precursors
por: de Sousa Lopes, Susana M Chuva, et al.
Publicado: (2007)

Esrrb Complementation Rescues Development of Nanog-Null Germ Cells
por: Zhang, Man, et al.
Publicado: (2018)

On the fate of primordial germ cells injected into early mouse embryos()
por: Leitch, Harry G., et al.
Publicado: (2014)

Publisher Correction: Tracing the transitions from pluripotency to germ cell fate with CRISPR screening
por: Hackett, Jamie A., et al.
Publicado: (2018)

Sequential enhancer state remodelling defines human germline competence and specification
por: Tang, Walfred W.C., et al.
Publicado: (2022)

A role for Lin28 in primordial germ cell development and germ cell malignancy
por: West, Jason A., et al.
Publicado: (2009)

Coordination of EZH2 and SOX2 specifies human neural fate decision
por: Zhao, Yuan, et al.
Publicado: (2021)

MicroRNA Biogenesis Is Required for Mouse Primordial Germ Cell Development and Spermatogenesis
por: Hayashi, Katsuhiko, et al.
Publicado: (2008)

Membrane-Bound Steel Factor Maintains a High Local Concentration for Mouse Primordial Germ Cell Motility, and Defines the Region of Their Migration
por: Gu, Ying, et al.
Publicado: (2011)

Specialized germline P-bodies are required to specify germ cell fate in Caenorhabditis elegans embryos
por: Cassani, Madeline, et al.
Publicado: (2022)

Metabolic regulation of pluripotency and germ cell fate through α‐ketoglutarate
por: Tischler, Julia, et al.
Publicado: (2018)

Derivation of hypermethylated pluripotent embryonic stem cells with high potency
por: Bao, Siqin, et al.
Publicado: (2018)

Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate
por: Stefanovic, Sonia, et al.
Publicado: (2009)

The fate of primordial magnetic monopoles
por: Lazarides, G, et al.
Publicado: (1980)

Activation of Lineage Regulators and Transposable Elements across a Pluripotent Spectrum
por: Hackett, Jamie A., et al.
Publicado: (2017)

Primordial Germ Cell Specification and Migration
por: Marlow, Florence
Publicado: (2015)

Zebrafish Primordial Germ Cell Migration
por: Aalto, Anne, et al.
Publicado: (2021)

EGL-13/SoxD Specifies Distinct O(2) and CO(2) Sensory Neuron Fates in Caenorhabditis elegans
por: Gramstrup Petersen, Jakob, et al.
Publicado: (2013)

Dose-dependent functions of fibroblast growth factor 9 regulate the fate of murine XY primordial germ cells(†)
por: Ulu, Ferhat, et al.
Publicado: (2017)

NICD-mediated notch transduction regulates the different fate of chicken primordial germ cells and spermatogonial stem cells
por: Zuo, Qisheng, et al.
Publicado: (2018)

Fate Decisions of Chicken Primordial Germ Cells (PGCs): Development, Integrity, Sex Determination, and Self-Renewal Mechanisms
por: Ichikawa, Kennosuke, et al.
Publicado: (2023)

The Origin And Migration Of Primordial Germ Cells In Sturgeons
por: Saito, Taiju, et al.
Publicado: (2014)

Primordial Germ Cells: Current Knowledge and Perspectives
por: Nikolic, Aleksandar, et al.
Publicado: (2016)

Enhanced cultivation of chicken primordial germ cells
por: Dehdilani, Nima, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_rgvrm8d61smife2qt7jjlqspr2