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Evaluating treatment response using DW-MRI and DCE-MRI in trastuzumab responsive and resistant HER2-overexpressing human breast cancer xenografts

We report longitudinal diffusion-weighted magnetic resonance imaging (DW-MRI) and dynamic contrast enhanced (DCE)-MRI (7 T) studies designed to identify functional changes, prior to volume changes, in trastuzumab-sensitive and resistant HER2 + breast cancer xenografts. Athymic mice (N = 33) were sub...

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Detalles Bibliográficos
Autores principales: Whisenant, Jennifer G., Sorace, Anna G., McIntyre, J. Oliver, Kang, Hakmook, Sánchez, Violeta, Loveless, Mary E., Yankeelov, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311041/
https://www.ncbi.nlm.nih.gov/pubmed/25500087
http://dx.doi.org/10.1016/j.tranon.2014.09.011