Antihyperglycemic mechanism of metformin occurs via the AMPK/LXRα/POMC pathway

Metformin is a first-line drug for treating type 2 diabetes. Although metformin is known to phosphorylate AMP-activated protein kinase (AMPK), it is unclear how the glucose-lowering effect of metformin is related to AMPK activation. The aim of this study was to identify the urinary endogenous metabo...

Descripción completa

Detalles Bibliográficos
Autores principales: Cho, Kumsun, Chung, Jae Yong, Cho, Sung Kweon, Shin, Hyun-Woo, Jang, In-Jin, Park, Jong-Wan, Yu, Kyung-Sang, Cho, Joo-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311245/
https://www.ncbi.nlm.nih.gov/pubmed/25634597
http://dx.doi.org/10.1038/srep08145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311245/
https://www.ncbi.nlm.nih.gov/pubmed/25634597
http://dx.doi.org/10.1038/srep08145

Ejemplares similares