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Theileria equi isolates vary in susceptibility to imidocarb dipropionate but demonstrate uniform in vitro susceptibility to a bumped kinase inhibitor

BACKGROUND: The apicomplexan hemoparasite Theileria equi is a causative agent of equine piroplasmosis, eradicated from the United States in 1988. However, recent outbreaks have sparked renewed interest in treatment options for infected horses. Imidocarb dipropionate is the current drug of choice, ho...

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Detalles Bibliográficos
Autores principales: Hines, Siddra A, Ramsay, Joshua D, Kappmeyer, Lowell S, Lau, Audrey OT, Ojo, Kayode K, Van Voorhis, Wesley C, Knowles, Donald P, Mealey, Robert H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311422/
https://www.ncbi.nlm.nih.gov/pubmed/25600252
http://dx.doi.org/10.1186/s13071-014-0611-6