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Optimization of the recombinant production and purification of a self-assembling peptide in Escherichia coli

BACKGROUND: Amphiphilic peptides are important building blocks to generate nanostructured biomaterials for drug delivery and tissue engineering applications. We have shown that the self-assembling peptide SA2 (Ac-AAVVLLLWEE) can be recombinantly produced in E. coli when fused to the small ubiquitin-...

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Detalles Bibliográficos
Autores principales: Rad-Malekshahi, Mazda, Flement, Matthias, Hennink, Wim E, Mastrobattista, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311431/
https://www.ncbi.nlm.nih.gov/pubmed/25551787
http://dx.doi.org/10.1186/s12934-014-0178-0