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Optimization of the recombinant production and purification of a self-assembling peptide in Escherichia coli
BACKGROUND: Amphiphilic peptides are important building blocks to generate nanostructured biomaterials for drug delivery and tissue engineering applications. We have shown that the self-assembling peptide SA2 (Ac-AAVVLLLWEE) can be recombinantly produced in E. coli when fused to the small ubiquitin-...
Autores principales: | Rad-Malekshahi, Mazda, Flement, Matthias, Hennink, Wim E, Mastrobattista, Enrico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311431/ https://www.ncbi.nlm.nih.gov/pubmed/25551787 http://dx.doi.org/10.1186/s12934-014-0178-0 |
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