Synthesis of antibacterial 1,3-diyne-linked peptoids from an Ugi-4CR/Glaser coupling approach

A library of ten 1,3-diyne-linked peptoids has been synthesized through an Ugi four-component reaction (U-4CR) followed by a copper-catalysed alkyne homocoupling (Glaser reaction). The short and chemoselective reaction sequence allows generating diverse (pseudo) dimeric peptoids. A combinatorial ver...

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Detalles Bibliográficos
Autores principales: Brauer, Martin C N, Neves Filho, Ricardo A W, Westermann, Bernhard, Heinke, Ramona, Wessjohann, Ludger A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311588/
https://www.ncbi.nlm.nih.gov/pubmed/25670988
http://dx.doi.org/10.3762/bjoc.11.4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311588/
https://www.ncbi.nlm.nih.gov/pubmed/25670988
http://dx.doi.org/10.3762/bjoc.11.4

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