NAA-modified DNA oligonucleotides with zwitterionic backbones: stereoselective synthesis of A–T phosphoramidite building blocks

Modifications of the nucleic acid backbone are essential for the development of oligonucleotide-derived bioactive agents. The NAA-modification represents a novel artificial internucleotide linkage which enables the site-specific introduction of positive charges into the otherwise polyanionic backbon...

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Detalles Bibliográficos
Autores principales: Schmidtgall, Boris, Höbartner, Claudia, Ducho, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311628/
https://www.ncbi.nlm.nih.gov/pubmed/25670992
http://dx.doi.org/10.3762/bjoc.11.8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311628/
https://www.ncbi.nlm.nih.gov/pubmed/25670992
http://dx.doi.org/10.3762/bjoc.11.8

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