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MRM-DIFF: data processing strategy for differential analysis in large scale MRM-based lipidomics studies

Based on theoretically calculated comprehensive lipid libraries, in lipidomics as many as 1000 multiple reaction monitoring (MRM) transitions can be monitored for each single run. On the other hand, lipid analysis from each MRM chromatogram requires tremendous manual efforts to identify and quantify...

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Detalles Bibliográficos
Autores principales: Tsugawa, Hiroshi, Ohta, Erika, Izumi, Yoshihiro, Ogiwara, Atsushi, Yukihira, Daichi, Bamba, Takeshi, Fukusaki, Eiichiro, Arita, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311682/
https://www.ncbi.nlm.nih.gov/pubmed/25688256
http://dx.doi.org/10.3389/fgene.2014.00471