Synthesis of divalent ligands of β-thio- and β-N-galactopyranosides and related lactosides and their evaluation as substrates and inhibitors of Trypanosoma cruzi trans-sialidase

In this work we describe the synthesis of mono- and divalent β-N- and β-S-galactopyranosides and related lactosides built on sugar scaffolds and their evaluation as substrates and inhibitors of the Trypanosoma cruzi trans-sialidase (TcTS). This enzyme catalyzes the transfer of sialic acid from an ol...

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Detalles Bibliográficos
Autores principales: Cano, María Emilia, Agusti, Rosalía, Cagnoni, Alejandro J, Tesoriero, María Florencia, Kovensky, José, Uhrig, María Laura, de Lederkremer, Rosa M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311708/
https://www.ncbi.nlm.nih.gov/pubmed/25670976
http://dx.doi.org/10.3762/bjoc.10.324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311708/
https://www.ncbi.nlm.nih.gov/pubmed/25670976
http://dx.doi.org/10.3762/bjoc.10.324

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