Canonical Wnt Pathway Inhibitor ICG-001 Induces Cytotoxicity of Multiple Myeloma Cells in Wnt-Independent Manner

Canonical Wnt signaling has been implicated in the regulation of multiple myeloma (MM) growth. Here, we investigated whether the targeting of this pathway with a novel pharmacological inhibitor ICG-001 would result in an anti-tumor effect and improvement of chemosensitivity in MM. As expected, ICG-0...

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Detalles Bibliográficos
Autores principales: Grigson, Eileen R., Ozerova, Maria, Pisklakova, Alexandra, Liu, Hao, Sullivan, Daniel M., Nefedova, Yulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311909/
https://www.ncbi.nlm.nih.gov/pubmed/25635944
http://dx.doi.org/10.1371/journal.pone.0117693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311909/
https://www.ncbi.nlm.nih.gov/pubmed/25635944
http://dx.doi.org/10.1371/journal.pone.0117693

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