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Direct NMR Detection of Bifurcated Hydrogen Bonding in the α-Helix N-Caps of Ankyrin Repeat Proteins

[Image: see text] In biomolecules, bifurcated H-bonds typically involve the interaction of two donor protons with the two lone pairs of oxygen. Here, we present direct NMR evidence for a bifurcated H-bonding arrangement involving nitrogen as the acceptor atom. Specifically, the H-bond network compri...

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Detalles Bibliográficos
Autores principales: Preimesberger, Matthew R., Majumdar, Ananya, Aksel, Tural, Sforza, Kevin, Lectka, Thomas, Barrick, Doug, Lecomte, Juliette T. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311973/
https://www.ncbi.nlm.nih.gov/pubmed/25578373
http://dx.doi.org/10.1021/ja510784g