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Photonic Activation of Plasminogen Induced by Low Dose UVB

Activation of plasminogen to its active form plasmin is essential for several key mechanisms, including the dissolution of blood clots. Activation occurs naturally via enzymatic proteolysis. We report that activation can be achieved with 280 nm light. A 2.6 fold increase in proteolytic activity was...

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Detalles Bibliográficos
Autores principales: Correia, Manuel, Snabe, Torben, Thiagarajan, Viruthachalam, Petersen, Steffen Bjørn, Campos, Sara R. R., Baptista, António M., Neves-Petersen, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312030/
https://www.ncbi.nlm.nih.gov/pubmed/25635856
http://dx.doi.org/10.1371/journal.pone.0116737