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Development and Validation of a Luminescence-based, Medium-Throughput Assay for Drug Screening in Schistosoma mansoni

BACKGROUND: Schistosomiasis, one of the world’s greatest neglected tropical diseases, is responsible for over 280,000 human deaths per annum. Praziquantel, developed in the 1970s, has high efficacy, excellent tolerability, few and transient side effects, simple administration procedures and competit...

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Detalles Bibliográficos
Autores principales: Lalli, Cristiana, Guidi, Alessandra, Gennari, Nadia, Altamura, Sergio, Bresciani, Alberto, Ruberti, Giovina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312041/
https://www.ncbi.nlm.nih.gov/pubmed/25635836
http://dx.doi.org/10.1371/journal.pntd.0003484