INMAP Overexpression Inhibits Cell Proliferation, Induces Genomic Instability and Functions through p53/p21 Pathways

INMAP is a spindle protein that plays essential role for mitosis, by ensuring spindle and centromere integrality. The aim of this study was to investigate the relevant functions of INMAP for genomic stability and its functional pathway. We overexpressed INMAP in HeLa cells, resulting in growth inhib...

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Detalles Bibliográficos
Autores principales: Zhu, Yan, Lei, Yan, Du, Baochen, Zheng, Yanbo, Lu, Xiangfeng, Tan, Tan, Kang, Jingting, Sun, Le, Liang, Qianjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312054/
https://www.ncbi.nlm.nih.gov/pubmed/25635878
http://dx.doi.org/10.1371/journal.pone.0115704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312054/
https://www.ncbi.nlm.nih.gov/pubmed/25635878
http://dx.doi.org/10.1371/journal.pone.0115704

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