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INMAP Overexpression Inhibits Cell Proliferation, Induces Genomic Instability and Functions through p53/p21 Pathways
INMAP is a spindle protein that plays essential role for mitosis, by ensuring spindle and centromere integrality. The aim of this study was to investigate the relevant functions of INMAP for genomic stability and its functional pathway. We overexpressed INMAP in HeLa cells, resulting in growth inhib...
Autores principales: | Zhu, Yan, Lei, Yan, Du, Baochen, Zheng, Yanbo, Lu, Xiangfeng, Tan, Tan, Kang, Jingting, Sun, Le, Liang, Qianjin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312054/ https://www.ncbi.nlm.nih.gov/pubmed/25635878 http://dx.doi.org/10.1371/journal.pone.0115704 |
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