A Critical Dose of Doxorubicin Is Required to Alter the Gene Expression Profiles in MCF-7 Cells Acquiring Multidrug Resistance

Cellular mechanisms of multidrug resistance (MDR) are related to ABC transporters, apoptosis, antioxidation, drug metabolism, DNA repair and cell proliferation. It remains unclear whether the process of resistance development is programmable. We aimed to study gene expression profiling circumstances...

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Detalles Bibliográficos
Autores principales: Tsou, Shang-Hsun, Chen, Tzer-Ming, Hsiao, Hui-Ting, Chen, Yen-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312059/
https://www.ncbi.nlm.nih.gov/pubmed/25635866
http://dx.doi.org/10.1371/journal.pone.0116747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312059/
https://www.ncbi.nlm.nih.gov/pubmed/25635866
http://dx.doi.org/10.1371/journal.pone.0116747

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