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A Critical Dose of Doxorubicin Is Required to Alter the Gene Expression Profiles in MCF-7 Cells Acquiring Multidrug Resistance
Cellular mechanisms of multidrug resistance (MDR) are related to ABC transporters, apoptosis, antioxidation, drug metabolism, DNA repair and cell proliferation. It remains unclear whether the process of resistance development is programmable. We aimed to study gene expression profiling circumstances...
Autores principales: | Tsou, Shang-Hsun, Chen, Tzer-Ming, Hsiao, Hui-Ting, Chen, Yen-Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312059/ https://www.ncbi.nlm.nih.gov/pubmed/25635866 http://dx.doi.org/10.1371/journal.pone.0116747 |
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