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A Co-Culture System with an Organotypic Lung Slice and an Immortal Alveolar Macrophage Cell Line to Quantify Silica-Induced Inflammation

There is growing evidence that amorphous silica nanoparticles cause toxic effects on lung cells in vivo as well as in vitro and induce inflammatory processes. The phagocytosis of silica by alveolar macrophages potentiates these effects. To understand the underlying molecular mechanisms of silica tox...

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Detalles Bibliográficos
Autores principales: Hofmann, Falk, Bläsche, Robert, Kasper, Michael, Barth, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312074/
https://www.ncbi.nlm.nih.gov/pubmed/25635824
http://dx.doi.org/10.1371/journal.pone.0117056