Molecular docking approaches in identification of High affinity inhibitors of Human SMO receptor

Inappropriate activation of the Hh signaling pathway has been implicated in the development of several types of cancers including prostate, lung, pancreas, breast, brain and skin. Present study identified the binding affinities of eight established inhibitors viz., Cyclopamine, Saridegib, Itraconazo...

Descripción completa

Detalles Bibliográficos
Autores principales: Akare, Uday Raj, Bandaru, Srinivas, Shaheen, Uzma, Singh, Pramod Kumar, Tiwari, Geet, Singare, Paramanand, Nayarisseri, Anuraj, Banerjee, Tushar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2014
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312366/
https://www.ncbi.nlm.nih.gov/pubmed/25670876
http://dx.doi.org/10.6026/97320630010737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312366/
https://www.ncbi.nlm.nih.gov/pubmed/25670876
http://dx.doi.org/10.6026/97320630010737

Ejemplares similares