Computer aided screening of potent inhibitor compounds against inhibitor resistant TEM β-lactamase mutants from traditional Chinese medicine

Inhibitor-resistant TEM (IRT) type β-lactamase mutation is largely known. Therefore, it is of interest to identify new yet improved leads against IRT from traditional Chinese medicine. Hence, we screened more than 10,000 compounds from Chinese medicine (tcm@taiwan database) with mutant molecular IRT...

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Detalles Bibliográficos
Autores principales: Zhu, Qifeng, Yin, Yanxia, Liu, Hanjie, Tian, Jinhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2014
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312368/
https://www.ncbi.nlm.nih.gov/pubmed/25670878
http://dx.doi.org/10.6026/97320630010750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312368/
https://www.ncbi.nlm.nih.gov/pubmed/25670878
http://dx.doi.org/10.6026/97320630010750

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