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Formulation and optimization of itraconazole polymeric lipid hybrid nanoparticles (Lipomer) using box behnken design
BACKGROUND: The objective of the study was to formulate and to investigate the combined influence of 3 independent variables in the optimization of Polymeric lipid hybrid nanoparticles (PLHNs) (Lipomer) containing hydrophobic antifungal drug Itraconazole and to improve intestinal permeability. METHO...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312448/ https://www.ncbi.nlm.nih.gov/pubmed/25604353 http://dx.doi.org/10.1186/s40199-014-0087-0 |