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Formulation and optimization of itraconazole polymeric lipid hybrid nanoparticles (Lipomer) using box behnken design

BACKGROUND: The objective of the study was to formulate and to investigate the combined influence of 3 independent variables in the optimization of Polymeric lipid hybrid nanoparticles (PLHNs) (Lipomer) containing hydrophobic antifungal drug Itraconazole and to improve intestinal permeability. METHO...

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Detalles Bibliográficos
Autores principales: Gajra, Balaram, Dalwadi, Chintan, Patel, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312448/
https://www.ncbi.nlm.nih.gov/pubmed/25604353
http://dx.doi.org/10.1186/s40199-014-0087-0