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Age dependent changes in the LPS induced transcriptome of bovine dermal fibroblasts occurs without major changes in the methylome

BACKGROUND: By comparing fibroblasts collected from animals at 5-months or 16-months of age we have previously found that the cultures from older animals produce much more IL-8 in response to lipopolysaccharide (LPS) stimulation. We now expand this finding by examining whole transcriptome difference...

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Detalles Bibliográficos
Autores principales: Green, Benjamin B, McKay, Stephanie D, Kerr, David E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312471/
https://www.ncbi.nlm.nih.gov/pubmed/25623529
http://dx.doi.org/10.1186/s12864-015-1223-z