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Periostin Secreted by Glioblastoma Stem Cells Recruits M2 Tumor-associated Macrophages and Promotes Malignant Growth

Tumor-associated macrophages (TAMs) are enriched in glioblastoma (GBM) that contains glioma stem cells (GSCs) at the apex of its cellular hierarchy. The correlation between TAM density and glioma grade suggests a supportive role of TAMs in tumor progression. Here we interrogated the molecular link b...

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Detalles Bibliográficos
Autores principales: Zhou, Wenchao, Ke, Susan Q., Huang, Zhi, Flavahan, William, Fang, Xiaoguang, Paul, Jeremy, Wu, Ling, Sloan, Andrew E., McLendon, Roger E., Li, Xiaoxia, Rich, Jeremy N., Bao, Shideng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312504/
https://www.ncbi.nlm.nih.gov/pubmed/25580734
http://dx.doi.org/10.1038/ncb3090