Cargando…

Innate immunity pathways regulate the nephropathy gene Apolipoprotein L1

Apolipoprotein L1 (APOL1) risk variants greatly elevate the risk of kidney disease in African Americans. Here we report a cohort of patients who developed collapsing focal segmental glomerulosclerosis while receiving therapeutic interferon, all of whom carried the APOL1 high-risk genotype. This find...

Descripción completa

Detalles Bibliográficos
Autores principales: Nichols, Brendan, Jog, Prachi, Lee, Jessica, Blackler, Daniel, Wilmot, Michael, D’Agati, Vivette, Markowitz, Glen, Kopp, Jeffrey, Alper, Seth L., Pollak, Martin R., Friedman, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312530/
https://www.ncbi.nlm.nih.gov/pubmed/25100047
http://dx.doi.org/10.1038/ki.2014.270