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Innate immunity pathways regulate the nephropathy gene Apolipoprotein L1
Apolipoprotein L1 (APOL1) risk variants greatly elevate the risk of kidney disease in African Americans. Here we report a cohort of patients who developed collapsing focal segmental glomerulosclerosis while receiving therapeutic interferon, all of whom carried the APOL1 high-risk genotype. This find...
Autores principales: | Nichols, Brendan, Jog, Prachi, Lee, Jessica, Blackler, Daniel, Wilmot, Michael, D’Agati, Vivette, Markowitz, Glen, Kopp, Jeffrey, Alper, Seth L., Pollak, Martin R., Friedman, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312530/ https://www.ncbi.nlm.nih.gov/pubmed/25100047 http://dx.doi.org/10.1038/ki.2014.270 |
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