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5-HT2B Receptor Antagonists Inhibit Fibrosis and Protect from RV Heart Failure

Objective. The serotonin (5-HT) pathway was shown to play a role in pulmonary hypertension (PH), but its functions in right ventricular failure (RVF) remain poorly understood. The aim of the current study was to investigate the effects of Terguride (5-HT2A and 2B receptor antagonist) or SB204741 (5-...

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Detalles Bibliográficos
Autores principales: Janssen, Wiebke, Schymura, Yves, Novoyatleva, Tatyana, Kojonazarov, Baktybek, Boehm, Mario, Wietelmann, Astrid, Luitel, Himal, Murmann, Kirsten, Krompiec, Damian Richard, Tretyn, Aleksandra, Pullamsetti, Soni Savai, Weissmann, Norbert, Seeger, Werner, Ghofrani, Hossein Ardeschir, Schermuly, Ralph Theo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312574/
https://www.ncbi.nlm.nih.gov/pubmed/25667920
http://dx.doi.org/10.1155/2015/438403