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5-HT2B Receptor Antagonists Inhibit Fibrosis and Protect from RV Heart Failure
Objective. The serotonin (5-HT) pathway was shown to play a role in pulmonary hypertension (PH), but its functions in right ventricular failure (RVF) remain poorly understood. The aim of the current study was to investigate the effects of Terguride (5-HT2A and 2B receptor antagonist) or SB204741 (5-...
Autores principales: | Janssen, Wiebke, Schymura, Yves, Novoyatleva, Tatyana, Kojonazarov, Baktybek, Boehm, Mario, Wietelmann, Astrid, Luitel, Himal, Murmann, Kirsten, Krompiec, Damian Richard, Tretyn, Aleksandra, Pullamsetti, Soni Savai, Weissmann, Norbert, Seeger, Werner, Ghofrani, Hossein Ardeschir, Schermuly, Ralph Theo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312574/ https://www.ncbi.nlm.nih.gov/pubmed/25667920 http://dx.doi.org/10.1155/2015/438403 |
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