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Iron homeostasis and tumorigenesis: molecular mechanisms and therapeutic opportunities
Excess iron is tightly associated with tumorigenesis in multiple human cancer types through a variety of mechanisms including catalyzing the formation of mutagenic hydroxyl radicals, regulating DNA replication, repair and cell cycle progression, affecting signal transduction in cancer cells, and act...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Higher Education Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312762/ https://www.ncbi.nlm.nih.gov/pubmed/25476483 http://dx.doi.org/10.1007/s13238-014-0119-z |