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Adjudin protects rodent cochlear hair cells against gentamicin ototoxicity via the SIRT3-ROS pathway

Hearing loss resulting from hair cell degeneration is a common disease that affects millions of people worldwide. Strategies to overcome the apparent irreversible hair cell loss in mammals become paramount for hearing protection. Here we reported that, by using a well-established gentamicin-induced...

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Detalles Bibliográficos
Autores principales: Quan, Yizhou, Xia, Li, Shao, Jiaxiang, Yin, Shankai, Cheng, C. Yan, Xia, Weiliang, Gao, Wei-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313083/
https://www.ncbi.nlm.nih.gov/pubmed/25640330
http://dx.doi.org/10.1038/srep08181