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An HDAC-dependent epigenetic mechanism that enhances the efficacy of the antidepressant drug fluoxetine
Depression is a prevalent and debilitating psychiatric illnesses. However, currently prescribed antidepressant drugs are only efficacious in a limited group of patients. Studies on Balb/c mice suggested that histone deacetylase (HDAC) inhibition may enhance the efficacy of the widely-prescribed anti...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313090/ https://www.ncbi.nlm.nih.gov/pubmed/25639887 http://dx.doi.org/10.1038/srep08171 |