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Cigarette smoke alters primary human bronchial epithelial cell differentiation at the air-liquid interface
The differentiated human airway epithelium consists of different cell types forming a polarized and pseudostratified epithelium. This is dramatically altered in chronic obstructive pulmonary disease (COPD), characterized by basal and goblet cell hyperplasia, and squamous cell metaplasia. The effect...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313097/ https://www.ncbi.nlm.nih.gov/pubmed/25641363 http://dx.doi.org/10.1038/srep08163 |