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Mammalian Cell Culture Process for Monoclonal Antibody Production: Nonlinear Modelling and Parameter Estimation

Monoclonal antibodies (mAbs) are at present one of the fastest growing products of pharmaceutical industry, with widespread applications in biochemistry, biology, and medicine. The operation of mAbs production processes is predominantly based on empirical knowledge, the improvements being achieved b...

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Detalles Bibliográficos
Autores principales: Selişteanu, Dan, Șendrescu, Dorin, Georgeanu, Vlad, Roman, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313526/
https://www.ncbi.nlm.nih.gov/pubmed/25685797
http://dx.doi.org/10.1155/2015/598721